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1 Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry and University Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK
2 Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, UK
3 Wolfson Research Institute for Health and Wellbeing, School of Medicine and Health, Durham University, Durham, UK
4 Leeds Institute of Health Sciences, Leeds University, Leeds, UK
5 Oxford Clinical Trials Research Unit, Nuffield Department of Orthopaedics, Rheumatology & Musculoskeletal Sciences, University of Oxford, Oxford, UK
* Corresponding author Email: Matthew.Costa@warwick.ac.uk
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