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Barnaby C Reeves, Katie Pike, Chris A Rogers, Rachel CM Brierley, Elizabeth A Stokes, Sarah Wordsworth, Rachel L Nash, Alice Miles, Andrew D Mumford, Alan Cohen, Gianni D Angelini, Gavin J Murphy & on behalf of the TITRe2 investigators.

Barnaby C Reeves 1,*, Katie Pike 1, Chris A Rogers 1, Rachel CM Brierley 1, Elizabeth A Stokes 2, Sarah Wordsworth 2, Rachel L Nash 1, Alice Miles 1, Andrew D Mumford 3, Alan Cohen 4, Gianni D Angelini 5, Gavin J Murphy 6,

1 Clinical Trials and Evaluation Unit, School of Clinical Sciences, University of Bristol, Bristol, UK
2 Health Economics Research Centre, Nuffield Department of Population Health, University of Oxford, Oxford, UK
3 School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK
4 Division of Specialised Services, University Hospitals Bristol NHS Foundation Trust, Bristol, UK
5 Bristol Heart Institute, School of Clinical Sciences, University of Bristol, Bristol, UK
6 Department of Cardiovascular Sciences and National Institute for Health Research Leicester Biomedical Research Unit in Cardiovascular Medicine, University of Leicester, Leicester, UK
* Corresponding author Email: barney.reeves@bristol.ac.uk

Transfusion Indication Threshold Reduction (TITRe2) investigators are listed in Appendix 1

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