Clinical and economic evaluation of laparoscopic surgery compared with medical management for gastro-oesophageal reflux disease: 5-year follow-up of multicentre randomised trial (the REFLUX trial)

doi:10.3310/hta17220

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Study found that, after 5 years, laparoscopic fundoplication gives sustained better relief of gastro-oesophageal reflux disease symptoms than continued medical management, with associated improved health-related quality of life, and that, despite being initially more costly, a surgical policy is highly likely to be cost-effective.

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