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1 Department of Ophthalmology, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle, UK
2 Institute of Neuroscience, Newcastle University, Newcastle, UK
3 Newcastle Clinical Trials Unit, Institute of Health and Society, Newcastle University, Newcastle, UK
4 Institute of Health and Society, Newcastle University, Newcastle, UK
5 Sunderland Eye Infirmary, City Hospitals Sunderland NHS Foundation Trust, Sunderland, UK
6 Moorfields Eye Hospital NHS Foundation Trust, London, UK
7 Department of Ophthalmology, York Hospitals NHS Foundation Trust, York, UK
8 Ophthalmology Department, Faculty of Medicine, Minia University, Al-Mini, Egypt
* Corresponding author Email: Michael.clarke@nuth.nhs.uk
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