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A randomised controlled trial to assess the clinical effectiveness and cost-effectiveness of alternative treatments to Inhibit VEGF in Age-related choroidal Neovascularisation (IVAN)

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Usha Chakravarthy, Simon P Harding, Chris A Rogers, Susan Downes, Andrew J Lotery, Helen A Dakin, Lucy Culliford, Lauren J Scott, Rachel L Nash, Jodi Taylor, Alyson Muldrew, Jayashree Sahni, Sarah Wordsworth, James Raftery, Tunde Peto, Barnaby C Reeves & for the IVAN Investigators.

Usha Chakravarthy 1,*, Simon P Harding 2, Chris A Rogers 3, Susan Downes 4, Andrew J Lotery 5, Helen A Dakin 6, Lucy Culliford 3, Lauren J Scott 3, Rachel L Nash 3, Jodi Taylor 3, Alyson Muldrew 1, Jayashree Sahni 2, Sarah Wordsworth 6, James Raftery 7, Tunde Peto 8, Barnaby C Reeves 3,

1 Centre for Experimental Medicine, Institute of Clinical Science, Queen’s University Belfast, Belfast, UK
2 Department of Eye and Vision Science, Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, UK
3 Clinical Trials and Evaluation Unit, School of Clinical Sciences, University of Bristol, Bristol, UK
4 Oxford University Hospitals NHS Trust, Oxford, UK
5 Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK
6 Health Economic Research Centre, Nuffield Department of Population Health, University of Oxford, Oxford, UK
7 Wessex Institute, University of Southampton, Southampton, UK
8 National Institute for Health Research (NIHR) Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK
* Corresponding author Email: u.chakravarthy@qub.ac.uk
Corresponding author Email:

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