Canagliflozin, dapagliflozin and empagliflozin monotherapy for treating type 2 diabetes: systematic review and economic evaluation

Johnston, Rhona; Uthman, Olalekan; Cummins, Ewen; Clar, Christine; Royle, Pamela; Colquitt, Jill; Tan, Bee Kang; Clegg, Andrew; Shantikumar, Saran; Court, Rachel; O’Hare, J Paul; McGrane, David; Holt, Tim; Waugh, Norman

doi:10.3310/hta21020

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Although dapagliflozin, canagliflozin and empagliflozin improve glycaemic control, as monotherapy they are not cost-effective compared to gliclazide or pioglitazone, but may be against sitagliptin.

Rhona Johnston, Olalekan Uthman, Ewen Cummins, Christine Clar, Pamela Royle, Jill Colquitt, Bee Kang Tan, Andrew Clegg, Saran Shantikumar, Rachel Court, J Paul O’Hare, David McGrane, Tim Holt & Norman Waugh.

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Rhona Johnston ¹, Olalekan Uthman ², Ewen Cummins ¹, Christine Clar ³, Pamela Royle ², Jill Colquitt ⁴, Bee Kang Tan ², Andrew Clegg ⁵, Saran Shantikumar ², Rachel Court ², J Paul O’Hare ², David McGrane ⁶, Tim Holt ⁷, Norman Waugh ^2,^*

¹ McMDC, Harrogate, UK
² Warwick Evidence, Division of Health Sciences, University of Warwick, Coventry, UK
³ , Berlin, Germany
⁴ Effective Evidence, Waterlooville, UK
⁵ University of Central Lancashire, Preston, UK
⁶ Queen Elizabeth University Hospital, Glasgow, UK
⁷ University of Oxford, Oxford, UK
^* Corresponding author Email: norman.waugh@warwick.ac.uk

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