Molecular testing for Lynch syndrome in people with colorectal cancer: systematic reviews and economic evaluation

Snowsill, Tristan; Coelho, Helen; Huxley, Nicola; Jones-Hughes, Tracey; Briscoe, Simon; Frayling, Ian M; Hyde, Chris

doi:10.3310/hta21510

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Microsatellite instability and immunohistochemistry will identify most cases of Lynch syndrome in colorectal cancer but there is no high-quality evidence that screening improves long-term outcomes

Tristan Snowsill, Helen Coelho, Nicola Huxley, Tracey Jones-Hughes, Simon Briscoe, Ian M Frayling & Chris Hyde.

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Tristan Snowsill ^1,^*, Helen Coelho ¹, Nicola Huxley ¹, Tracey Jones-Hughes ¹, Simon Briscoe ¹, Ian M Frayling ², Chris Hyde ¹

¹ Peninsula Technology Assessment Group (PenTAG), University of Exeter, Exeter, UK
² Institute of Cancer and Genetics, University Hospital of Wales, Cardiff, UK
^* Corresponding author Email: t.m.snowsill@exeter.ac.uk

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