Gastrostomy versus nasogastric tube feeding for chemoradiation patients with head and neck cancer: the TUBE pilot RCT

Paleri, Vinidh; Patterson, Joanne; Rousseau, Nikki; Moloney, Eoin; Craig, Dawn; Tzelis, Dimitrios; Wilkinson, Nina; Franks, Jeremy; Hynes, Ann Marie; Heaven, Ben; Hamilton, David; Guerrero-Urbano, Teresa; Donnelly, Rachael; Barclay, Stewart; Rapley, Tim; Stocken, Deborah

doi:10.3310/hta22160

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The trial did not meet one of the three criteria for progression, with recruitment less than half of that planned although once recruited, patient compliance and retention were both high.

Vinidh Paleri , Joanne Patterson , Nikki Rousseau , Eoin Moloney , Dawn Craig , Dimitrios Tzelis , Nina Wilkinson , Jeremy Franks , Ann Marie Hynes , Ben Heaven , David Hamilton , Teresa Guerrero-Urbano , Rachael Donnelly , Stewart Barclay , Tim Rapley & Deborah Stocken .

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Vinidh Paleri ^1,^2,^3,^*, Joanne Patterson ⁴, Nikki Rousseau ⁴, Eoin Moloney ⁴, Dawn Craig ⁴, Dimitrios Tzelis ⁴, Nina Wilkinson ⁵, Jeremy Franks ⁴, Ann Marie Hynes ⁶, Ben Heaven ⁴, David Hamilton ⁴, Teresa Guerrero-Urbano ⁷, Rachael Donnelly ⁷, Stewart Barclay ⁸, Tim Rapley ⁴, Deborah Stocken ^5,⁹

¹ Head and Neck Unit, The Royal Marsden Hospital, London, UK
² Division of Clinical Studies, Institute of Cancer Research, London, UK
³ Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, UK
⁴ Institute of Health and Society, Newcastle University, Newcastle upon Tyne, UK
⁵ Biostatistics Research group, Institute of Health and Society, Newcastle University, Newcastle upon Tyne, UK
⁶ Newcastle Clinical Trials Unit, Newcastle University, Newcastle upon Tyne, UK
⁷ Department of Radiation Oncology, Guy’s and St Thomas’ NHS Foundation Trust, London, UK
⁸ Department of Restorative Dentistry, The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK
⁹ Leeds Institute of Clinical Trials Research, University of Leeds, Leeds, UK
^* Corresponding author Email: vinidh.paleri@rmh.nhs.uk

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