Negative-pressure wound therapy compared with standard dressings following surgical treatment of major trauma to the lower limb: the WHiST RCT

Costa, Matthew L; Achten, Juul; Knight, Ruth; Png, May Ee; Bruce, Julie; Dutton, Susan; Madan, Jason; Vadher, Karan; Dritsaki, Melina; Masters, James; Spoors, Louise; Campolier, Marta; Parsons, Nick; Fernandez, Miguel; Jones, Suzanne; Grant, Richard; Nanchahal, Jagdeep

doi:10.3310/hta24380

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There was no evidence of a difference between incisional negative-pressure wound therapy and standard dressings in the rate of deep surgical site infection at 30 days.

Matthew L Costa , Juul Achten , Ruth Knight , May Ee Png , Julie Bruce , Susan Dutton , Jason Madan , Karan Vadher , Melina Dritsaki , James Masters , Louise Spoors , Marta Campolier , Nick Parsons , Miguel Fernandez , Suzanne Jones , Richard Grant & Jagdeep Nanchahal .

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Matthew L Costa ^1,^*, Juul Achten ¹, Ruth Knight ², May Ee Png ², Julie Bruce ³, Susan Dutton ², Jason Madan ³, Karan Vadher ², Melina Dritsaki ², James Masters ¹, Louise Spoors ¹, Marta Campolier ¹, Nick Parsons ⁴, Miguel Fernandez ¹, Suzanne Jones ⁵, Richard Grant ⁵, Jagdeep Nanchahal ¹

¹ Oxford Trauma, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK
² Oxford Clinical Trials Research Unit, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK
³ Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, UK
⁴ Statistics and Epidemiology Unit, Warwick Medical School, University of Warwick, Coventry, UK
⁵ Patient and public involvement group member, ,
^* Corresponding author Email: matthew.costa@ndorms.ox.ac.uk

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