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Despite limited empirical evidence on which to base a protocol, this study provides a reference protocol for health technology assessment and a framework for generating reference protocols in other settings.
1 Centre for Health Economics, University of York, York, UK
2 Department of Management Science, University of Strathclyde, Glasgow, UK
3 MRC Biostatistics Unit, University of Cambridge, Cambridge, UK
4 London School of Hygiene & Tropical Medicine, London, UK
5 Leeds University Business School, Leeds, UK
* Corresponding author Email: Laura.bojke@york.ac.uk
Declared competing interests of authors: Laura Bojke declares private consulting for BresMed (Sheffield, UK) and Roboleo & Co (Brackley, UK), not related to the current work. Alec Morton declares private consulting for AstraZeneca (Cambridge, UK) and Office of Health Economics (London, UK), not related to the current work. Alec Morton and Abigail Colson were previously supported by that European Union 7th Framework Programme that received in-kind support from pharmaceutical companies, including Astellas Pharma Inc. (Tokyo, Japan), Roche (Basel, Switzerland) and AstraZeneca.
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