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This study showed that graduated compression stockings (and other mechanical compression methods) reduced the risk of deep venous thrombosis and pulmonary embolism in a wide range of surgical patients. Oral anticoagulants (such as warfarin) and infusions of dextran were also effective, although they appeared less protective than heparin-based regimens. In operations where regional anaesthesia is feasible, it resulted in a lower risk of venous thromboembolism than general anaesthesia, thus adding to any benefits from mechanical and pharmacologic methods.
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