Alitretinoin versus phototherapy as the first-line treatment in adults with severe chronic hand eczema: the ALPHA RCT

Wittmann, Miriam; Smith, Isabelle L; Brown, Sarah Tess; Berekméri, Anna; Vargas-Palacios, Armando; Sunderland, Lesley; Barker, Amy; Cowdell, Fiona; Ersser, Steven; Gilberts, Rachael; Green, Cathy; Hampton, Philip; Smith, Catherine; Nixon, Jane

doi:10.3310/TWQC0141

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Miriam Wittmann , Isabelle L Smith , Sarah Tess Brown , Anna Berekméri , Armando Vargas-Palacios , Lesley Sunderland , Amy Barker , Fiona Cowdell , Steven Ersser , Rachael Gilberts , Cathy Green , Philip Hampton , Catherine Smith & Jane Nixon .

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Miriam Wittmann ^1,^2,^*, Isabelle L Smith ³, Sarah Tess Brown ³, Anna Berekméri ^1,⁴, Armando Vargas-Palacios ⁵, Lesley Sunderland ⁶, Amy Barker ⁷, Fiona Cowdell ⁸, Steven Ersser ⁹, Rachael Gilberts ³, Cathy Green ¹⁰, Philip Hampton ¹¹, Catherine Smith ¹², Jane Nixon ^3,⁵

¹ Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, Yorkshire, UK
² University Medical Centre of Johannes Gutenberg University Mainz, Mainz, Germany
³ Clinical Trials Research Unit, Leeds Institute of Clinical Trials Research, University of Leeds, Leeds, UK
⁴ NIHR Leeds Musculoskeletal Biomedical Research Unit (LMBRU), Chapel Allerton Hospital, Leeds, UK
⁵ Academic Unit of Health Economics, Leeds Institute of Health Sciences, University of Leeds, Leeds, UK
⁶ Street Lane Practice, Roundhay, Leeds, UK
⁷ Patient representative, Leeds, UK
⁸ Faculty of Health Education and Life Sciences, Birmingham City University, Birmingham, UK
⁹ Department of Nursing Science, Faculty of Health and Social Science, Bournemouth University, Bournemouth, UK
¹⁰ Department of Dermatology, Ninewells Hospital, Dundee, Tayside, UK
¹¹ Department of Dermatology, Newcastle Hospital, Newcastle, Tyne and Wear, UK
¹² St John’s Institute of Dermatology, Guy’s and St Thomas’s NHS Foundation Trust, London, UK
^* Corresponding author Email: Miriam.Wittmann@unimedizin-mainz.de

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