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1 Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Botnar Research Centre, University of Oxford, Headington, Oxford, UK
2 Nuffield Department of Population Health, University of Oxford, Oxford, UK
3 Nuffield Orthopaedic Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK
4 Swansea Bay University Health Board, Swansea, UK
5 Heatherwood and Wexham Park Hospitals, Frimley Health NHS Foundation Trust, Slough, UK
6 College of Medicine and Health, University of Exeter, Exeter, UK
7 Fr3dom Ltd, Brighton, UK
8 Royal Berkshire Hospital, Royal Berkshire NHS Foundation Trust, Reading, UK
9 University College Hospitals, University College London Hospitals NHS Foundation Trust, London, UK
10 University Hospital of Wales, Cardiff and Vale University Health Board, Cardiff, UK
* Corresponding author Email: david.beard@ndorms.ox.ac.uk
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