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This study found both multiple and single risk behaviour interventions for people with severe mental illness were associated with positive but modest benefits on most outcomes.

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Nick Meader 1,*, Hollie Melton 1, Connor Evans 1, Kath Wright 1, David Shiers 2,3, Elena Ratschen 4, Sofia Dias 1, Ceri Dare 5, Gordon Johnston 5,6, Harminder Kaur 5, Michel Syrett 5,6, Christopher J Armitage 7,8, Rachel Churchill 1, Simon Gilbody 4, Peter Coventry 1,4

1 Centre for Reviews and Dissemination, University of York, York, UK
2 Division of Psychology and Mental Health, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK
3 Psychosis Research Unit, Greater Manchester Mental Health NHS Foundation Trust, Manchester, UK
4 Department of Health Sciences, University of York, York, UK
5 HEALTH study patient and public involvement group, , UK
6 Lived Experience Research Collective, HEALTH study patient and public involvement group, , UK
7 Division of Psychology and Mental Health, University of Manchester, Manchester, UK
8 Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK
* Corresponding author Email: nick.meader@york.ac.uk

Declared competing interests of authors: Rachel Churchill is a current member of the systematic reviews programme advisory group. Simon Gilbody is a member of the following National Institute for Health Research (NIHR) committees: Health Technology Assessment (HTA) Postfunding Committee teleconference (2017–20), Funding Committee Policy Group (2017–20) and HTA Commissioning Committee (2016–20). David Shiers reports personal fees as a clinical advisor to the National Clinical Audit of Psychosis (NCAP), and personal fees from the Wiley-Blackwell publication Promoting Recovery in Early Psychosis: A Practice Manual (2010, ISBN 978-1-4051-4894-8), as a joint editor in receipt of royalties, outside the submitted work. He is also an expert advisor to the National Institute for Health and Care Excellence (NICE)’s centre for guidelines and a member of the current NICE guideline development group for rehabilitation in adults with complex psychosis, a board member of the National Collaborating Centre for Mental Health (NCCMH), and a clinical advisor (paid consultancy basis) to NCAP. Elena Ratschen reports grants from the NIHR Programme Grants for Applied Research programme (NIHR200607) and grants from Cancer Research UK, outside the submitted work; she is also a co-opted topic expert on smoking and mental health on a NICE committee developing the new NICE tobacco guideline suite. Sofia Dias reports grants from NIHR during the conduct of the study (NIHR131946). Christopher J Armitage is supported by the NIHR Manchester Biomedical Research Centre and by the NIHR Greater Manchester Patient Safety Translational Research Centre. Peter Coventry is a member of the following committees: HTA General Board (2018–19) and Health and Social Care Delivery Research Funding Committee (2019–present).

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