The impact of opiate substitution treatment on mortality risk in drug addicts: a natural experiment study

Steer, Colin D; Macleod, John; Tilling, Kate; Lim, Aaron G; Marsden, John; Millar, Tim; Strang, John; Telfer, Maggie; Whitaker, Heather; Vickerman, Peter; Hickman, Matthew

doi:10.3310/hsdr07030

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There was evidence that the treatment period risks varied with the medication, but buprenorphine as an alternative to methadone may not reduce mortality overall due to shorter treatment duration.

Colin D Steer , John Macleod , Kate Tilling , Aaron G Lim , John Marsden , Tim Millar , John Strang , Maggie Telfer , Heather Whitaker , Peter Vickerman & Matthew Hickman .

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Colin D Steer ^1,^*, John Macleod ¹, Kate Tilling ¹, Aaron G Lim ¹, John Marsden ², Tim Millar ³, John Strang ², Maggie Telfer ⁴, Heather Whitaker ⁵, Peter Vickerman ¹, Matthew Hickman ¹

¹ Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK
² National Addiction Centre, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London, UK
³ Centre for Mental Health and Safety, School of Health Sciences, University of Manchester, Manchester, UK
⁴ Bristol Drug Project, Bristol, UK
⁵ Department of Mathematics and Statistics, The Open University, Milton Keynes, UK
^* Corresponding author Email: Colin.Steer@bristol.ac.uk

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