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Linda Sharples, Priya Sastry, Carol Freeman, Joanne Gray, Andrew McCarthy, Yi-Da Chiu, Colin Bicknell, Peter McMeekin, S Rao Vallabhaneni, Andrew Cook, Luke Vale & Stephen Large.

Linda Sharples ^1,*, Priya Sastry ², Carol Freeman ³, Joanne Gray ⁴, Andrew McCarthy ⁴, Yi-Da Chiu ^3,5, Colin Bicknell ⁶, Peter McMeekin ⁴, S Rao Vallabhaneni ⁷, Andrew Cook ^8,9, Luke Vale ¹⁰, Stephen Large ¹¹

¹ Department of Medical Statistics, London School of Hygiene and Tropical Medicine, London, UK
² Department of Cardiac Surgery, John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK
³ Papworth Trials Unit Collaboration, Royal Papworth Hospital NHS Foundation Trust, Cambridge, UK
⁴ Faculty of Health and Life Sciences, Northumbria University, Newcastle upon Tyne, UK
⁵ Medical Research Council (MRC) Biostatistics Unit, School of Clinical Medicine, University of Cambridge, Cambridge, UK
⁶ Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, London, UK
⁷ Liverpool Vascular & Endovascular Service, Royal Liverpool University Hospital, Liverpool, UK
⁸ Wessex Institute, University of Southampton, Southampton, UK
⁹ Southampton Clinical Trials Unit, University of Southampton, Southampton, UK
¹⁰ Health Economics Group, Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK
¹¹ Department of Cardiac Surgery, Royal Papworth Hospital NHS Foundation Trust, Cambridge, UK
^* Corresponding author Email: Linda.Sharples@lshtm.ac.uk

Declared competing interests of authors: S Rao Vallabhaneni reports unrestricted research grants from Cook Medical (Bloomington, IN, USA) and Terumo Aortic (UK) (Vascutek Ltd, Inchinnan, UK) during the conduct of the study. Colin Bicknell reports personal fees and non-financial support from Medtronic plc (Dublin, Ireland) and grants, personal fees and non-financial support from W. L. Gore & Associates, Inc. (Newark, DE, USA), all outside the submitted work. Luke Vale reports that he was a member of the NIHR Health Technology Assessment Clinical Trials and Evaluation Panel (2015–18).