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Adrian Murray Brunt 1,2,*, Joanne S Haviland 2, Duncan A Wheatley 3, Mark A Sydenham 2, David J Bloomfield 4, Charlie Chan 5, Suzy Cleator 6, Charlotte E Coles 7, Ellen Donovan 8, Helen Fleming 9, David Glynn 10, Andrew Goodman 11, Susan Griffin 10, Penelope Hopwood 2, Anna M Kirby 12, Cliona C Kirwan 13, Zohal Nabi 14, Jaymini Patel 2, Elinor Sawyer 15, Navita Somaiah 12, Isabel Syndikus 16, Karen Venables 14, John R Yarnold 12, Judith M Bliss 2

1 School of Medicine, University of Keele and University Hospitals of North Midlands, Staffordshire, UK
2 Clinical Trials and Statistics Unit (ICR-CTSU), The Institute of Cancer Research, London, UK
3 Department of Oncology, Royal Cornwall Hospital NHS Trust, Truro, UK
4 Sussex Cancer Centre, Brighton and Sussex University Hospitals, Brighton, UK
5 Women’s Health Clinic, Nuffield Health Cheltenham Hospital, Cheltenham, UK
6 Department of Oncology, Imperial Healthcare NHS Trust, London, UK
7 Department of Oncology, University of Cambridge, Cambridge, UK
8 Centre for Vision, Speech and Signal Processing, University of Surrey, Guildford, UK
9 Clinical and Translational Radiotherapy Research Group, National Cancer Research Institute, London, UK
10 Centre for Health Economics, University of York, York, UK
11 Oncology Unit, Torbay Hospital, Devon, UK
12 Department of Radiotherapy, The Royal Marsden NHS Foundation Trust, Sutton, UK
13 Division of Cancer Sciences, University of Manchester, Manchester, UK
14 RTQQA, Mount Vernon Cancer Centre, Middlesex, UK
15 Comprehensive Cancer Centre, King’s College London, London, UK
16 Clatterbridge Cancer Centre, Clatterbridge Hospital NHS Trust, Cheshire, UK
* Corresponding author Emails: m.brunt@keele.ac.uk and fastforward-icrctsu@icr.ac.uk

Declared competing interests of authors

Full disclosure of interests: Completed ICMJE forms for all authors, including all related interests, are available in the toolkit on the NIHR Journals Library report publication page at https://doi.org/10.3310/WWBF1044.

Primary conflicts of interest: Joanne Haviland reports grant funding from NIHR HTA (London, UK) and is a member of the HTA Clinical Evaluation and Trials Committee (2019–23). Duncan Wheatley reports personal fees from Roche (Basel, Switzerland) and Daiichi Sankyo (Tokyo, Japan) and travel support from Roche (Basel, Switzerland). Mark Sydenham reports grant funding from NIHR HTA (London, UK). David Bloomfield reports personal fees from Astra Zeneca (Cambridge, UK). Charlotte Coles reports a NIHR Research Professorship and is a member of HTA Clinical Evaluation and Trials Committee (2017–23). Ellen Donovan reports grant funding from NIHR-HTA (London, UK). David Glynn reports grant funding from NIHR-HTA (London, UK) and from Cancer Research UK (London, UK). Susan Griffin reports grant funding from NIHR-HTA (London, UK) and is a member of PHR Research Funding Board (2022–26). Anna Kirby reports grant funding from Cancer Research UK (London, UK) and is President of the European Society of Radiation Oncology. Zohal Nabi reports grant funding from NIHR-HTA (London, UK). Jaymini Patel reports grant funding from NIHR-HTA (London, UK). Isabel Syndikus reports personal fees from Bayer (Leverkusen, Germany), Pfizer (Sandwich, UK), Astellas (Tokyo, Japan), Janssen (High Wycombe, UK) and travel support from Bayer (Leverkusen, Germany), Roche (Basel, Switzerland). She is a member of the Data Monitoring and Safety Committee for Bristol Myers Squibb (New York City, USA). Karen Venables reports grant funding from NIHR (London, UK) and is a member of the RTTQA management group. Judith Bliss reports grants from NIHR-HTA (London, UK), Astra Zeneca (Cambridge, UK), Merck Sharp Dohme (New Jersey, USA), Puma Biotechnology (Los Angeles, USA), Clovis Oncology (Boulder, USA), Pfizer (Sandwich, UK), Janssen-Cilag (High Wycombe, UK), Novartis (Basel, Switzerland), Roche (Basel, Switzerland), Eli Lilly (Indianapolis, USA) and an AACR Scientific Achievement Award and Honorarium 2022. She is a NIHR Senior Researcher and is a member of the HTA Commissions Committee (2011–16).

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