Deferasirox for the treatment of iron overload associated with regular blood transfusions (transfusional hemosiderosis) in patients suffering with chronic anaemia: a systematic review and economic evaluation

McLeod, C; Fleeman, N; Kirkham, J; Bagust, A; Boland, A; Chu, P; Dickson, R; Dundar, Y; Greenhalgh, J; Modell, B; Olujohungbe, A; Telfer, P; Walley, T

doi:10.3310/hta13010

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Study found that, in the short term, there is little clinical difference between deferasirox, deferoxamine and deferiprone in terms of removing iron from the blood and liver, and that deferasirox may be cost-effective compared with deferoxamine in patients with beta-thalassaemia and sickle cell disease but is unlikely to be cost-effective compared with deferiprone

C McLeod, N Fleeman, J Kirkham, A Bagust, A Boland, P Chu, R Dickson, Y Dundar, J Greenhalgh, B Modell, A Olujohungbe, P Telfer & T Walley.

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C McLeod ¹, N Fleeman ¹, J Kirkham ², A Bagust ³, A Boland ¹, P Chu ⁴, R Dickson ^1,^*, Y Dundar ¹, J Greenhalgh ¹, B Modell ⁵, A Olujohungbe ⁶, P Telfer ⁷, T Walley ¹

¹ Liverpool Reviews and Implementation Group, University of Liverpool, , UK
² Centre for Medical Statistics and Health Evaluation, University of Liverpool, , UK
³ University of Liverpool Management School, Liverpool, UK
⁴ Royal Liverpool University Hospital, Liverpool, UK
⁵ University College London, , UK
⁶ University Hospital Aintree, Liverpool, UK
⁷ Queen Mary, University of London, , UK
^* Corresponding author Email: r.dickson@liv.ac.uk

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