A systematic review and economic evaluation of the clinical effectiveness and cost-effectiveness of aldosterone antagonists for postmyocardial infarction heart failure

McKenna, C; Burch, J; Suekarran, S; Walker, S; Bakhai, A; Witte, K; Harden, M; Wright, K; Woolacott, N; Lorgelly, P; Fenwick, L; Palmer, S

doi:10.3310/hta14240

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Treatment with aldosterone antagonists such as eplerenone and spironolactone are likely to be highly cost-effective uses of NHS resources for the management of postmyocardial infarction heart failure. Further research is warranted on the relative benefits of one aldosterone antagonist over the other.

C McKenna, J Burch, S Suekarran, S Walker, A Bakhai, K Witte, M Harden, K Wright, N Woolacott, P Lorgelly, L Fenwick & S Palmer.

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C McKenna ^1,^*, J Burch ², S Suekarran ², S Walker ¹, A Bakhai ³, K Witte ⁴, M Harden ², K Wright ², N Woolacott ², P Lorgelly ⁵, L Fenwick ⁵, S Palmer ¹

¹ Centre for Health Economics, University of York, York, UK
² Centre for Reviews and Dissemination, University of York, York, UK
³ Barnet General Hospital, Barnet, UK
⁴ University of Leeds and Leeds General Infirmary, Leeds, UK
⁵ Section of Health Policy and Public Health, University of Glasgow, Glasgow, UK
^* Corresponding author Email: cm535@york.ac.uk

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