The clinical effectiveness and cost-effectiveness of different surveillance mammography regimens after the treatment for primary breast cancer: systematic reviews, registry database analyses and economic evaluation

Robertson, C; Arcot Ragupathy, SK; Boachie, C; Dixon, JM; Fraser, C; Hernández, R; Heys, S; Jack, W; Kerr, GR; Lawrence, G; MacLennan, G; Maxwell, A; McGregor, J; Mowatt, G; Pinder, S; Ternent, L; Thomas, RE; Vale, L; Wilson, R; Zhu, S; Gilbert, FJ

doi:10.3310/hta15340

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Review finds that surveillance following treatment of primary breast cancer is likely to improve patient survival, with a strategy of mammography alone every 12–24 months appearing to have the highest net benefits. To optimise the use of resources and achieve maximum patient benefit, women at a higher risk of developing ipsilateral breast tumour recurrence or metachronous contralateral breast cancer should be offered more comprehensive and more frequent surveillance.

C Robertson, SK Arcot Ragupathy, C Boachie, JM Dixon, C Fraser, R Hernández, S Heys, W Jack, GR Kerr, G Lawrence, G MacLennan, A Maxwell, J McGregor, G Mowatt, S Pinder, L Ternent, RE Thomas, L Vale, R Wilson, S Zhu & FJ Gilbert.

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C Robertson ^1,^*, SK Arcot Ragupathy ², C Boachie ¹, JM Dixon ³, C Fraser ¹, R Hernández ^1,⁴, S Heys ⁵, W Jack ³, GR Kerr ⁶, G Lawrence ⁷, G MacLennan ¹, A Maxwell ⁸, J McGregor ⁹, G Mowatt ¹, S Pinder ¹⁰, L Ternent ^1,³, RE Thomas ¹, L Vale ^1,³, R Wilson ¹¹, S Zhu ¹, FJ Gilbert ¹²

¹ Health Services Research Unit, University of Aberdeen, Aberdeen, UK
² Radiology Department, Aberdeen Royal Infirmary, NHS Grampian, Aberdeen, UK
³ Edinburgh Breast Unit, Edinburgh Cancer Centre, Western General Hospital, Edinburgh, UK
⁴ Health Economics Research Unit, University of Aberdeen, Aberdeen, UK
⁵ Division of Applied Medicine, School of Medicine and Dentistry, University of Aberdeen, Aberdeen, UK
⁶ Department of Clinical Oncology, Edinburgh Cancer Centre, Western General Hospital, Edinburgh, UK
⁷ West Midlands Cancer Intelligence Unit, Birmingham Women’s NHS Foundation Trust, Birmingham, UK
⁸ Breast Unit, Royal Bolton Hospital, Bolton, UK
⁹ Breast Cancer Care, London, UK
¹⁰ Research Oncology, Kings College, London, UK
¹¹ Department of Clinical Radiology, The Royal Marsden, Sutton, UK
¹² Aberdeen Biomedical Imaging Centre, University of Aberdeen, and Aberdeen Royal Infirmary, NHS Grampian, Aberdeen, UK
^* Corresponding author Email: c.robertson@abdn.ac.uk

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