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1 Clinical Trials Unit, Intensive Care National Audit & Research Centre, London, UK
2 Departments of Surgery and Emergency Medicine, Washington University, St Louis, MO, USA
3 Department of Health Services Research and Policy, London School of Hygiene and Tropical Medicine, London, UK
4 Faculty of Medicine, Imperial College London, London, UK
5 Department of Acute Medicine, Chelsea and Westminster Hospital NHS Foundation Trust, London, UK
6 Department of Intensive Care Medicine, University of Birmingham, Birmingham, UK
7 Department of Cardiovascular Sciences, University of Leicester, Leicester, UK
8 Bloomsbury Institute of Intensive Care Medicine, University College London, London, UK
9 Nuffield Division of Anaesthetics, University of Oxford, Oxford, UK
* Corresponding author Email: kathy.rowan@icnarc.org
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