A cluster randomised trial, cost-effectiveness analysis and psychosocial evaluation of insulin pump therapy compared with multiple injections during flexible intensive insulin therapy for type 1 diabetes: the REPOSE Trial

Heller, Simon; White, David; Lee, Ellen; Lawton, Julia; Pollard, Daniel; Waugh, Norman; Amiel, Stephanie; Barnard, Katharine; Beckwith, Anita; Brennan, Alan; Campbell, Michael; Cooper, Cindy; Dimairo, Munyaradzi; Dixon, Simon; Elliott, Jackie; Evans, Mark; Green, Fiona; Hackney, Gemma; Hammond, Peter; Hallowell, Nina; Jaap, Alan; Kennon, Brian; Kirkham, Jackie; Lindsay, Robert; Mansell, Peter; Papaioannou, Diana; Rankin, David; Royle, Pamela; Smithson, W Henry; Taylor, Carolin

doi:10.3310/hta21200

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Adding pump therapy to structured training in flexible insulin therapy did not significantly enhance glycaemic control or psychosocial outcomes in adults with type 1 diabetes.

Simon Heller, David White, Ellen Lee, Julia Lawton, Daniel Pollard, Norman Waugh, Stephanie Amiel, Katharine Barnard, Anita Beckwith, Alan Brennan, Michael Campbell, Cindy Cooper, Munyaradzi Dimairo, Simon Dixon, Jackie Elliott, Mark Evans, Fiona Green, Gemma Hackney, Peter Hammond, Nina Hallowell, Alan Jaap, Brian Kennon, Jackie Kirkham, Robert Lindsay, Peter Mansell, Diana Papaioannou, David Rankin, Pamela Royle, W Henry Smithson & Carolin Taylor.

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Simon Heller ^1,^*, David White ², Ellen Lee ², Julia Lawton ³, Daniel Pollard ⁴, Norman Waugh ⁵, Stephanie Amiel ⁶, Katharine Barnard ⁷, Anita Beckwith ⁸, Alan Brennan ⁴, Michael Campbell ⁴, Cindy Cooper ², Munyaradzi Dimairo ², Simon Dixon ⁴, Jackie Elliott ¹, Mark Evans ^9,¹⁰, Fiona Green ¹¹, Gemma Hackney ², Peter Hammond ¹², Nina Hallowell ³, Alan Jaap ¹³, Brian Kennon ¹⁴, Jackie Kirkham ³, Robert Lindsay ¹⁵, Peter Mansell ¹⁶, Diana Papaioannou ², David Rankin ³, Pamela Royle ⁵, W Henry Smithson ¹⁷, Carolin Taylor ¹⁸

¹ Academic Unit of Diabetes, Endocrinology and Metabolism, University of Sheffield, Sheffield, UK
² Clinical Trials Research Unit, University of Sheffield, Sheffield, UK
³ Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK
⁴ School of Health and Related Research, University of Sheffield, Sheffield, UK
⁵ Division of Health Sciences, Warwick Medical School, University of Warwick, Coventry, UK
⁶ Diabetes Research Group, King’s College London, London, UK
⁷ Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK
⁸ King’s College Hospital NHS Foundation Trust, London, UK
⁹ Institute of Metabolic Science, University of Cambridge, Cambridge, UK
¹⁰ Wolfson Diabetes Clinic, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK
¹¹ Dumfries Royal Infirmary NHS Trust, Dumfries, UK
¹² Harrogate and District NHS Foundation Trust, Harrogate, UK
¹³ Edinburgh Centre for Endocrinology and Diabetes, Royal Infirmary of Edinburgh, Edinburgh, UK
¹⁴ Queen Elizabeth University Hospital, NHS Greater Glasgow and Clyde, Glasgow, UK
¹⁵ Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK
¹⁶ Nottingham University Hospitals NHS Trust, Nottingham, UK
¹⁷ Department of General Practice, University College Cork, Cork, Ireland
¹⁸ Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK
^* Corresponding author Email: s.heller@sheffield.ac.uk

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