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This feasibility study established a potential design for an RCT of early switching from intravenous to oral antibiotics for children with acute osteomyelitis or septic arthritis.
1 National Institute for Health Research Wellcome Trust Clinical Research Facility, University of Southampton, Southampton, UK
2 University Hospital Southampton NHS Foundation Trust, Southampton, UK
3 Medicines for Children Clinical Trials Unit, Clinical Trials Research Centre, Department of Biostatistics, University of Liverpool, Liverpool, UK
4 Public Health England, Southampton, UK
5 Health and Wellbeing Research and Development Group, University of Winchester, Winchester, UK
6 Radiology, Leeds Children’s Hospital, Leeds Teaching Hospitals NHS Trust, Leeds, UK
7 Norfolk and Norwich University Hospitals NHS Foundation Trust, Norwich, UK
8 Alder Hey Children’s NHS Foundation Trust, Liverpool, UK
9 Section of Paediatrics, Imperial College London, St Mary’s Campus, London, UK
10 Heart of England NHS Foundation Trust, Birmingham, UK
11 Paediatric Infectious Diseases, Great Ormond Street Hospital for Children, London, UK
12 Academic Unit of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK
13 Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle, UK
14 St George’s University Hospitals NHS Foundation Trust, London, UK
15 Bristol Children’s Vaccine Centre, School of Clinical Sciences, University of Bristol, Bristol, UK
16 Paediatric Infectious Diseases and Immunology, Bristol Royal Hospital for Children, Bristol, UK
17 Department of Paediatrics, Medical Sciences Division, University of Oxford, Oxford, UK
18 School of Medicine, University of Cardiff, Cardiff, UK
19 Department of Paediatrics, University Hospital of Wales, Cardiff, UK
20 Public Health England, South East Public Health England Regional Laboratory, Southampton, UK
21 Faculty of Health Sciences, University of Southampton, Southampton, UK
22 Paediatric Orthopaedics, University of Southampton, Southampton, UK
* Corresponding author Email: s.faust@soton.ac.uk
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