Spot protein-creatinine ratio and spot albumin-creatinine ratio in the assessment of pre-eclampsia: a diagnostic accuracy study with decision-analytic model-based economic evaluation and acceptability analysis

Waugh, Jason; Hooper, Richard; Lamb, Edmund; Robson, Stephen; Shennan, Andrew; Milne, Fiona; Price, Christopher; Thangaratinam, Shakila; Berdunov, Vladislav; Bingham, Jenn

doi:10.3310/hta21610

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This study does not support the use of 24 hour urine samples in predicting severe pre-eclampsia and the most cost-effective option was spot albumin creatinine ratio.

Jason Waugh , Richard Hooper , Edmund Lamb, Stephen Robson , Andrew Shennan , Fiona Milne , Christopher Price , Shakila Thangaratinam , Vladislav Berdunov & Jenn Bingham .

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Jason Waugh ^1,^*, Richard Hooper ², Edmund Lamb ³, Stephen Robson ⁴, Andrew Shennan ⁵, Fiona Milne ⁶, Christopher Price ⁷, Shakila Thangaratinam ², Vladislav Berdunov ², Jenn Bingham ⁸

¹ The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK
² Centre for Primary Care and Public Health, Queen Mary University of London, London, UK
³ East Kent Hospitals University NHS Foundation Trust, Canterbury, UK
⁴ Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK
⁵ Women’s Academic Health Centre, King’s College London, London, UK
⁶ Lay representative, ,
⁷ Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK
⁸ Newcastle Clinical Trials Unit, Newcastle University, Newcastle upon Tyne, UK
^* Corresponding author Email: jason.waugh@nuth.nhs.uk

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