Is whole-colon investigation by colonoscopy, computerised tomography colonography or barium enema necessary for all patients with colorectal cancer symptoms, and for which patients would flexible sigmoidoscopy suffice? A retrospective cohort study

Atkin, Wendy; Wooldrage, Kate; Shah, Urvi; Skinner, Kate; Brown, Jeremy P; Hamilton, Willie; Kralj-Hans, Ines; Thompson, Michael R; Flashman, Karen G; Halligan, Steve; Thomas-Gibson, Siwan; Vance, Margaret; Cross, Amanda J

doi:10.3310/hta21660

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In patients referred to hospital with suspected colorectal cancer, symptom profiles are associated with cancer site and can be used to decide the type of diagnostic examination to be performed.

Wendy Atkin, Kate Wooldrage, Urvi Shah, Kate Skinner, Jeremy P Brown, Willie Hamilton, Ines Kralj-Hans, Michael R Thompson, Karen G Flashman, Steve Halligan, Siwan Thomas-Gibson, Margaret Vance & Amanda J Cross.

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Wendy Atkin ^1,^*, Kate Wooldrage ¹, Urvi Shah ¹, Kate Skinner ¹, Jeremy P Brown ¹, Willie Hamilton ², Ines Kralj-Hans ¹, Michael R Thompson ³, Karen G Flashman ³, Steve Halligan ⁴, Siwan Thomas-Gibson ^1,⁵, Margaret Vance ⁵, Amanda J Cross ¹

¹ Department of Surgery and Cancer, Imperial College London, London, UK
² Institute of Health Research, University of Exeter Medical School, Exeter, UK
³ Department of Colorectal Surgery, Queen Alexandra Hospital, Portsmouth Hospitals NHS Trust, Portsmouth, UK
⁴ University College London Centre for Medical Imaging, University College London, London, UK
⁵ Wolfson Unit for Endoscopy, St Mark’s Hospital, London, UK
^* Corresponding author Email: w.atkin@imperial.ac.uk

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