Clinical effectiveness and cost-effectiveness of issuing longer versus shorter duration (3-month vs. 28-day) prescriptions in patients with chronic conditions: systematic review and economic modelling

Miani, Céline; Martin, Adam; Exley, Josephine; Doble, Brett; Wilson, Ed; Payne, Rupert; Avery, Anthony; Meads, Catherine; Kirtley, Anne; Jones, Molly Morgan; King, Sarah

doi:10.3310/hta21780

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For patients with stable chronic conditions in primary care, there is some evidence to suggest that 3-month prescriptions are less costly overall and associated with better adherence than 28-day prescriptions.

Céline Miani , Adam Martin , Josephine Exley , Brett Doble , Ed Wilson , Rupert Payne , Anthony Avery , Catherine Meads , Anne Kirtley , Molly Morgan Jones & Sarah King .

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Céline Miani ¹, Adam Martin ^1,², Josephine Exley ^1,^*, Brett Doble ^3,⁴, Ed Wilson ³, Rupert Payne ⁵, Anthony Avery ⁶, Catherine Meads ^1,⁷, Anne Kirtley ^1,⁸, Molly Morgan Jones ¹, Sarah King ⁹

¹ Cambridge Centre for Health Services Research, RAND Europe, Cambridge, UK
² Academic Unit of Health Economics, Leeds Institute of Health Sciences, University of Leeds, Leeds, UK
³ Cambridge Centre for Health Services Research, Cambridge Institute of Public Health, School of Clinical Medicine, University of Cambridge, Cambridge, UK
⁴ Health Economics Research Centre, Nuffield Department of Population Health, University of Oxford, Oxford, UK
⁵ Centre for Academic Primary Care, School of Social and Community Medicine, University of Bristol, Bristol, UK
⁶ School of Medicine, University of Nottingham, Nottingham, UK
⁷ School of Nursing and Midwifery, Faculty of Health, Social Care and Education, Anglia Ruskin University, Cambridge, UK
⁸ Strategy Division, Wellcome Trust, London, UK
⁹ Cambridge Institute of Public Health, School of Clinical Medicine, University of Cambridge, Cambridge, UK
^* Corresponding author Email: jexley@rand.org

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