What is the added value of ultrasound joint examination for monitoring synovitis in rheumatoid arthritis and can it be used to guide treatment decisions? A systematic review and cost-effectiveness analysis

Simpson, Emma; Hock, Emma; Stevenson, Matt; Wong, Ruth; Dracup, Naila; Wailoo, Allan; Conaghan, Philip; Estrach, Cristina; Edwards, Christopher; Wakefield, Richard

doi:10.3310/hta22200

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Limited evidence suggests ultrasound monitoring of synovitis could provide an effective approach to selecting rheumatoid arthritis patients for biologic treatment tapering or escalation-avoidance.

Emma Simpson , Emma Hock , Matt Stevenson , Ruth Wong , Naila Dracup , Allan Wailoo , Philip Conaghan , Cristina Estrach , Christopher Edwards & Richard Wakefield .

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Emma Simpson ^1,^*, Emma Hock ¹, Matt Stevenson ¹, Ruth Wong ¹, Naila Dracup ¹, Allan Wailoo ¹, Philip Conaghan ^2,³, Cristina Estrach ⁴, Christopher Edwards ⁵, Richard Wakefield ^2,³

¹ School of Health and Related Research (ScHARR), University of Sheffield, Sheffield, UK
² Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK
³ National Institute for Health Research (NIHR) Leeds Biomedical Research Centre, Leeds, UK
⁴ Aintree University Hospitals NHS Foundation Trust, Liverpool, UK
⁵ National Institute for Health Research (NIHR) Wellcome Trust Clinical Research Facility, University of Southampton, Southampton, UK
^* Corresponding author Email: e.l.simpson@sheffield.ac.uk

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