Bariatric surgery, lifestyle interventions and orlistat for severe obesity: the REBALANCE mixed-methods systematic review and economic evaluation

Avenell, Alison; Robertson, Clare; Skea, Zoë; Jacobsen, Elisabet; Boyers, Dwayne; Cooper, David; Aceves-Martins, Magaly; Retat, Lise; Fraser, Cynthia; Aveyard, Paul; Stewart, Fiona; MacLennan, Graeme; Webber, Laura; Corbould, Emily; Xu, Benshuai; Jaccard, Abbygail; Boyle, Bonnie; Duncan, Eilidh; Shimonovich, Michal; Bruin, Marijn de

doi:10.3310/hta22680

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Weight management programmes generally cost less than £20,000/QALY and bariatric surgery, though costly, was the most effective and cost-effective strategy over a 30-year time horizon.

Alison Avenell , Clare Robertson , Zoë Skea , Elisabet Jacobsen , Dwayne Boyers , David Cooper , Magaly Aceves-Martins , Lise Retat , Cynthia Fraser , Paul Aveyard , Fiona Stewart , Graeme MacLennan , Laura Webber , Emily Corbould , Benshuai Xu , Abbygail Jaccard , Bonnie Boyle , Eilidh Duncan , Michal Shimonovich & Marijn de Bruin .

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Alison Avenell ^1,^*, Clare Robertson ¹, Zoë Skea ¹, Elisabet Jacobsen ², Dwayne Boyers ², David Cooper ¹, Magaly Aceves-Martins ¹, Lise Retat ³, Cynthia Fraser ¹, Paul Aveyard ⁴, Fiona Stewart ¹, Graeme MacLennan ¹, Laura Webber ³, Emily Corbould ³, Benshuai Xu ³, Abbygail Jaccard ³, Bonnie Boyle ¹, Eilidh Duncan ¹, Michal Shimonovich ¹, Marijn de Bruin ⁵

¹ Health Services Research Unit, University of Aberdeen, Aberdeen, UK
² Health Economics Research Unit, University of Aberdeen, Aberdeen, UK
³ UK Health Forum, London, UK
⁴ Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK
⁵ Health Psychology, University of Aberdeen, Aberdeen, UK
^* Corresponding author Email: a.avenell@abdn.ac.uk

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