Tumour profiling tests to guide adjuvant chemotherapy decisions in early breast cancer: a systematic review and economic analysis

Harnan, Sue; Tappenden, Paul; Cooper, Katy; Stevens, John; Bessey, Alice; Rafia, Rachid; Ward, Sue; Wong, Ruth; Stein, Robert C; Brown, Janet

doi:10.3310/hta23300

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This study looked at five tests and, while there are limitations and uncertainty in the evidence, it suggests that all five can provide prognostic information although the estimates of cost/QALY varied widely.

Sue Harnan , Paul Tappenden , Katy Cooper , John Stevens , Alice Bessey , Rachid Rafia , Sue Ward , Ruth Wong , Robert C Stein & Janet Brown.

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Sue Harnan ^1,^*, Paul Tappenden ¹, Katy Cooper ¹, John Stevens ¹, Alice Bessey ¹, Rachid Rafia ¹, Sue Ward ¹, Ruth Wong ¹, Robert C Stein ^2,³, Janet Brown ⁴

¹ Health Economics and Decision Science, School of Health and Related Research, University of Sheffield, Sheffield, UK
² University College London Hospitals Biomedical Research Centre, London, UK
³ Research Department of Oncology, University College London, London, UK
⁴ Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK
^* Corresponding author Email: s.harnan@sheffield.ac.uk

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