Different strategies for pharmacological thromboprophylaxis for lower-limb immobilisation after injury: systematic review and economic evaluation

Pandor, Abdullah; Horner, Daniel; Davis, Sarah; Goodacre, Steve; Stevens, John W; Clowes, Mark; Hunt, Beverley J; Nokes, Tim; Keenan, Jonathan; de Wit, Kerstin

doi:10.3310/hta23630

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Thromboprophylaxis for all is clinically effective, with a cost per QALY of about £13,500, but could be optimised by using a risk assessment tool with sensitivity about 89% and specificity about 55%.

Abdullah Pandor , Daniel Horner , Sarah Davis , Steve Goodacre , John W Stevens , Mark Clowes , Beverley J Hunt , Tim Nokes , Jonathan Keenan & Kerstin de Wit .

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Abdullah Pandor ¹, Daniel Horner ², Sarah Davis ¹, Steve Goodacre ^1,^*, John W Stevens ¹, Mark Clowes ¹, Beverley J Hunt ³, Tim Nokes ⁴, Jonathan Keenan ⁴, Kerstin de Wit ⁵

¹ School of Health and Related Research (ScHARR), University of Sheffield, Sheffield, UK
² Emergency Department, Salford Royal NHS Foundation Trust, Salford, UK
³ Haemostasis Research Unit, King’s College London, London, UK
⁴ Department of Haematology, University Hospitals Plymouth NHS Trust, Plymouth, UK
⁵ Department of Medicine, Hamilton General Hospital, Hamilton, ON, Canada
^* Corresponding author Email: s.goodacre@sheffield.ac.uk

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