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The antibiotic-impregnated ventriculoperitoneal shunt reduced infection whereas the silver did not; the antibiotic shunt is likely to be cost-saving.
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Conor L Mallucci, Michael D Jenkinson, Elizabeth J Conroy, John C Hartley, Michaela Brown, Tracy Moitt, Joanne Dalton, Tom Kearns, Michael J Griffiths, Giovanna Culeddu, Tom Solomon, Dyfrig Hughes, Carrol Gamble & the BASICS study collaboratorsMallucciConor LPrincipal InvestigatorAlder Hey Children’s NHS Foundation TrustLiverpoolUKSolankiGuirishPrincipal InvestigatorBirmingham Children’s HospitalBirminghamUKEdwardsRichardPrincipal InvestigatorFrenchay HospitalBristolUKWilliamsAdamCo-principal InvestigatorFrenchay HospitalBristolUKGarnettMatthewCo-principal InvestigatorAddenbrooke’s HospitalCambridgeUKKoliasAngelosCo-principal InvestigatorAddenbrooke’s HospitalCambridgeUKLeachPaulPrincipal InvestigatorUniversity Hospital of WalesCardiffUKCrimminsDarachPrincipal InvestigatorTemple Street Children’s University HospitalDublinRepublic of IrelandCairdJohnCo-principal InvestigatorTemple Street Children’s University HospitalDublinRepublic of IrelandThompsonDominicPrincipal InvestigatorGreat Ormond Street HospitalLondonUKStrachanRogerPrincipal InvestigatorJames Cook University HospitalMiddleboroughUKZebianBasselPrincipal InvestigatorKing’s College HospitalLondonUKThakurBhaskarCo-principal InvestigatorKing’s College HospitalLondonUKGooddenJohnPrincipal InvestigatorLeeds General InfirmaryLeedsUKTomaAhmedPrincipal InvestigatorNational Hospital for Neurology and NeurosurgeryLondonUKHollimanDamianPrincipal InvestigatorNewcastle General HospitalNewcastle upon TyneUKCoulterIanCo-principal InvestigatorNewcastle General HospitalNewcastle upon TyneUKMacarthurDonaldPrincipal InvestigatorQueen’s Medical CentreNottinghamUKKamalyIanPrincipal InvestigatorRoyal Manchester Children’s HospitalManchesterUKKingAndrewPrincipal InvestigatorSalford Royal HospitalSalfordUKNadigArdashCo-principal InvestigatorSalford Royal HospitalSalfordUKUshewokunzeShunguPrincipal InvestigatorSheffield Children’s Hospital and Sheffield Teaching Hospitals NHS Foundation TrustSheffieldUKSinhaSaurabhCo-principal InvestigatorSheffield Children’s Hospital and Sheffield Teaching Hospitals NHS Foundation TrustSheffieldUKBultersDiederikPrincipal InvestigatorSouthampton General HospitalSouthamptonUKWatersRyanCo-principal InvestigatorSouthampton General HospitalSouthamptonUKJenkinsonMichael DPrincipal InvestigatorWalton CentreLiverpoolUKKandasamyJothyPrincipal InvestigatorWestern General HospitalEdinburghUKHughesMarkCo-principal InvestigatorWestern General HospitalEdinburghUK.
Conor L Mallucci 1,*, Michael D Jenkinson 2,3, Elizabeth J Conroy 4, John C Hartley 5, Michaela Brown 4, Tracy Moitt 4, Joanne Dalton 4, Tom Kearns 4, Michael J Griffiths 6,7, Giovanna Culeddu 8, Tom Solomon 6,9, Dyfrig Hughes 8, Carrol Gamble 4, †
1 Department of Paediatric Neurosurgery, Alder Hey Children’s NHS Foundation Trust, Liverpool, UK
2 Department of Neurosurgery, The Walton Centre NHS Foundation Trust, Liverpool, UK
3 Institute of Translational Medicine, University of Liverpool, Liverpool, UK
4 Liverpool Clinical Trials Centre, University of Liverpool, Liverpool, UK
5 Department of Microbiology, Great Ormond Street Hospital for Children, London, UK
6 Institute of Infection and Global Health, University of Liverpool, Liverpool, UK
7 Department of Paediatric Neurology, Alder Hey Children’s NHS Foundation Trust, Liverpool, UK
8 Centre for Health Economics and Medicines Evaluation, Bangor University, Bangor, UK
9 Department of Neurology, The Walton Centre NHS Foundation Trust, Liverpool, UK
* Corresponding author Email: cmallucci@me.com
† The BASICS study collaborators can be found in Appendix 1.
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