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This trial found no evidence of additional benefit of miconazole-rifampicin impregnated peripherally inserted central venous catheters during neonatal care, compared with standard, non-impregnated catheters.
1 UCL Great Ormond Street Institute of Child Health, Faculty of Population Health Sciences, University College London, London, UK
2 Health Data Research UK, London, UK
3 Liverpool Clinical Trials Centre, University of Liverpool, Liverpool, UK
4 Centre for Health Economics, University of York, York, UK
5 Barts Health NHS Trust, London, UK
6 Division of Neonatal–Perinatal Medicine, Dalhousie University IWK Health Centre, Halifax, NS, Canada
7 Birmingham Women’s and Children’s NHS Foundation Trust, Birmingham, UK
8 National Infection Service, Public Health England, London, UK
9 Centre for Reviews and Dissemination, University of York, York, UK
10 Bradford Neonatology, Bradford Royal Infirmary, Bradford, UK
* Corresponding author Email: r.gilbert@ucl.ac.uk
Declared competing interests of authors: Ruth Gilbert receives funding from Health Data Research UK. Ajay K Sinha reports that he was a member of the Health Technology Assessment (HTA) Women and Children Health panel between January 2017 and January 2018, during the conduct of the study. Jon Dorling reports grants from the National Institute for Health Research (NIHR) during the conduct of the study, outside the submitted work (RP-PG-0609-10107); Jon Dorling was also a member of the NIHR HTA General Board (from 2017 to 2018) and the NIHR HTA Maternity, Newborn and Child Health Panel (from 2013 to 2018). He was also funded by Nutrinia Ltd (Ramat Gan, Israel) in 2017 and 2018 for part of his salary to work as an expert advisor on a trial of enteral insulin. Katie Harron reports grants from the Wellcome Trust (grant number 103975/A/14/Z) during the conduct of the study. William McGuire reports membership of the HTA Commissioning Committee during the life of the project, and membership of the HTA and Efficacy and Mechanism Evaluation (EME) programme editorial boards. Laura Bojke is a member of the NIHR Health Services and Delivery Research researcher-led panel for stage 1 proposals (November 2019 to present). Carrol Gamble is a member of the EME funding board (November 2019 to present).
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