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Joseph Shalhoub, Rebecca Lawton, Jemma Hudson, Christopher Baker, Andrew Bradbury, Karen Dhillon, Tamara Everington, Manjit S Gohel, Zaed Hamady, Beverly J Hunt, Gerard Stansby, David Warwick, John Norrie & Alun H Davies.

Joseph Shalhoub ¹, Rebecca Lawton ¹, Jemma Hudson ², Christopher Baker ³, Andrew Bradbury ⁴, Karen Dhillon ³, Tamara Everington ⁵, Manjit S Gohel ^1,6, Zaed Hamady ⁷, Beverly J Hunt ⁸, Gerard Stansby ⁹, David Warwick ¹⁰, John Norrie ¹¹, Alun H Davies ^1,*

¹ Department of Surgery and Cancer, Imperial College London, London, UK
² Health Services Research Unit, University of Aberdeen, Aberdeen, UK
³ Department of Surgery and Cancer, Imperial College Healthcare NHS Trust, London, UK
⁴ College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK
⁵ Department of Haematology, Hampshire Hospitals NHS Foundation Trust, Basingstoke, UK
⁶ Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK
⁷ Southampton HPB Unit, University Hospital Southampton NHS Foundation Trust, Southampton, UK
⁸ Department of Thrombosis and Haemostasis, Guy’s & St Thomas’ NHS Foundation Trust, London, UK
⁹ Northern Vascular Unit, Freeman Hospital, The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK
¹⁰ Department of Trauma and Orthopaedic Surgery, University Hospital Southampton NHS Foundation Trust, Southampton, UK
¹¹ Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK
^* Corresponding author Email: a.h.davies@imperial.ac.uk

Declared competing interests of authors: Alun H Davies reports other grants from the National Institute for Health Research (NIHR), the Stroke Association (London, UK), The Graham–Dixon Charitable Trust, Sir Halley Stewart Trust, the J P Moulton Charitable Foundation, Laboratoires URGO SA (Chenõve, France) and Actegy Health Ltd (Bracknell, UK) during the conduct of the study, none of which is related to the submitted work. Manjit S Gohel reports personal fees and Advisory Board speaker fees from Medtronic plc (Dublin, Ireland) and from Cook Medical (Bloomington, IN, USA), and grants from Laboratoires URGO SA outside the submitted work. John Norrie reports membership of the following NIHR boards: Commissioning Priority Review Decision-making Committee (2015); Health Technology Assessment (HTA) Commissioning Board (2010–16); HTA Commissioning Sub-board (expression of interest) (2014); HTA Funding Boards Policy Group (2016–19); HTA General Board (2016–19); HTA post-board funding teleconference (2016–19); NIHR Clinical Trials Unit Standing Advisory Committee (2018 to present); NIHR HTA and Efficacy and Mechanism Evaluation Editorial Board (2014–19); and the Pre-exposure Prophylaxis Impact Review Panel (2017). Andrew Bradbury and Joseph Shalhoub report grants from NIHR during the conduct of the study.