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This study found little evidence to support the use of patches, but a wide variety of patches in use, and produced agreement on the outline of two potential randomised trials.
1 Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK
2 Health Experiences Research Group, Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK
3 National Institute for Health Research, Oxford Biomedical Research Centre, Oxford, UK
4 The James Cook University Hospital, South Tees Hospitals NHS Foundation Trust, Middlesbrough, UK
5 Patient representative, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK
6 Frimley Health NHS Foundation Trust, Frimley, UK
* Corresponding author Email: jonathan.cook@csm.ox.ac.uk
Declared competing interests of authors: Jonathan A Cook reports various grants from the National Institute for Health Research (NIHR), including studies funded by the Health Technology Assessment (HTA) programme and a project funded by NIHR Invention for Innovation evaluating an electrospun patch to augment rotator cuff tendon repair. He was a member of the NIHR HTA programme’s Efficient Trial Designs, and End of life Care and Add-on Studies boards between 2014 and 2016. Joanna C Crocker reports grants from the NIHR HTA programme during the conduct of the study and grants, personal fees and non-financial support from the University of Oxford outside the submitted work. Sally Hopewell has been a member of the HTA Clinical Evaluation and Trials committee from 1 November 2018 to present. Amar Rangan reports various grants from NIHR, Orthopaedic Research UK (London, UK), DePuy Synthes (Raynham, MA, USA) and Horizon 2020 outside the submitted work. Lucksy Kottam reports various grants from NIHR and DePuy Synthes outside the submitted work. Andrew J Carr reports the following grants from NIHR: Senior Investigator Award, Biomedical Research Centre (Musculoskeletal Disease) and the i4i programme grant ‘A novel electrospun patch to augment rotator cuff tendon repair’.
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