High-sensitivity troponin assays for early rule-out of acute myocardial infarction in people with acute chest pain: a systematic review and economic evaluation

Westwood, Marie; Ramaekers, Bram; Grimm, Sabine; Worthy, Gill; Fayter, Debra; Armstrong, Nigel; Buksnys, Titas; Ross, Janine; Joore, Manuela; Kleijnen, Jos

doi:10.3310/hta25330

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High-sensitivity troponin assays may be more cost-effective than standard troponin testing, and strategies involving multiple tests are likely to be more effective than a single test.

Marie Westwood , Bram Ramaekers , Sabine Grimm , Gill Worthy , Debra Fayter , Nigel Armstrong , Titas Buksnys , Janine Ross , Manuela Joore & Jos Kleijnen .

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Marie Westwood ^1,^*, Bram Ramaekers ², Sabine Grimm ², Gill Worthy ¹, Debra Fayter ¹, Nigel Armstrong ¹, Titas Buksnys ¹, Janine Ross ¹, Manuela Joore ², Jos Kleijnen ^1,³

¹ Kleijnen Systematic Reviews Ltd, York, UK
² Department of Clinical Epidemiology and Medical Technology Assessment, Maastricht University, Maastricht, the Netherlands
³ School for Public Health and Primary Care, Care and Public Health Research Institute, Maastricht University, Maastricht, the Netherlands
^* Corresponding author Email: marie@systematic-reviews.com

Declared competing interests of authors: none

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