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Jo Worthington, Jessica Frost, Emily Sanderson, Madeleine Cochrane, Jessica Wheeler, Nikki Cotterill, Stephanie J MacNeill, Sian Noble, Miriam Avery, Samantha Clarke, Mandy Fader, Hashim Hashim, Lucy McGeagh, Margaret Macaulay, Jonathan Rees, Luke Robles, Gordon Taylor, Jodi Taylor, Joanne Thompson, J Athene Lane, Matthew J Ridd & Marcus J Drake.

Jo Worthington ^1,†, Jessica Frost ^1,†, Emily Sanderson ¹, Madeleine Cochrane ¹, Jessica Wheeler ², Nikki Cotterill ³, Stephanie J MacNeill ¹, Sian Noble ², Miriam Avery ⁴, Samantha Clarke ⁵, Mandy Fader ⁴, Hashim Hashim ⁶, Lucy McGeagh ⁷, Margaret Macaulay ⁴, Jonathan Rees ⁸, Luke Robles ⁷, Gordon Taylor ⁹, Jodi Taylor ¹, Joanne Thompson ⁵, J Athene Lane ¹, Matthew J Ridd ¹⁰, Marcus J Drake ^6,11,*

¹ Bristol Trials Centre, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK
² Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK
³ School of Health and Social Wellbeing, College of Health, Science and Society, University of the West of England, Bristol, UK
⁴ School of Health Sciences, University of Southampton, Southampton, UK
⁵ Clinical Research Centre, Southmead Hospital, North Bristol NHS Trust, Bristol, UK
⁶ Bristol Urological Institute, Southmead Hospital, North Bristol NHS Trust, Bristol, UK
⁷ National Institute for Health and Care Research Bristol Biomedical Research Centre, University Hospitals Bristol and Weston NHS Foundation Trust, University of Bristol, Bristol, UK
⁸ Tyntesfield Medical Group, Bristol, UK
⁹ Patient and public involvement representative, , UK
¹⁰ Centre of Academic Primary Care, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK
¹¹ Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK
^* Corresponding author Email: Marcus.Drake@bristol.ac.uk

^† Contributed equally

Disclosure of interests

Contributed equally

Full disclosure of interests: Completed ICMJE forms for all authors, including all related interests, are available in the toolkit on the NIHR Journals Library report publication page at https://doi.org/10.3310/GVBC3182.

Primary conflicts of interest: Stephanie J MacNeill is an active member of the Health Technology Assessment (HTA) General Committee. Hashim Hashim reports personal fees from Medtronic plc (Dublin, Ireland), Astellas Pharma Inc. (Tokyo, Japan), Allergan plc (Dublin, Ireland) and Boston Scientific (Marlborough, MA, USA), outside the submitted work. Jonathan Rees is chairperson of the Primary Care Urology Society, which has received non-promotional sponsorship for annual meetings from Ferring Pharmaceuticals (Saint Prex, Switzerland), Astellas Pharma, NeoTract Inc. (Pleasanton, CA, USA) and iMEDicare Ltd (London Colney, UK). He has also received speaker fees from Astellas Pharma. J Athene Lane reports receiving funding from the clinical trials unit of which she was co-director, and is currently an active member of the National Institute for Health and Care Research (NIHR) Clinical Trials Unit Standing Advisory Committee. Matthew J Ridd was, during the course of the study, on several NIHR committees, namely the HTA General Committee and the Evidence Synthesis Programme Grants Committee, and is currently on the Evidence Synthesis Programme Advisory Group. Marcus J Drake reports personal fees from Astellas Pharma and Pfizer Inc. (New York, NY, USA), outside the submitted work.